SONTAL Marine Collagen Tripeptide (Veg CAPSULES)
Pack Size: 60 Vegetable Capsules
Each capsule contains 500 mg of Standardised 15% Tripeptide Collagen.
SONTAL Marine Collagen Tripeptide PIL
SONTAL Marine Collagen Tripeptide (CAPSULES)
Pack Size: 60 Vegetable Capsules
Each capsule contains 500 mg of 15% Tripeptide Collagen (as *Morikol®) – *Morikol® the registered trademark of DolCas Biotech, LLC USA.
Contains No Excipients.
This unregistered medicine has not been evaluated by the SAHPRA for its quality, safety or intended use.
Category D: Complementary Medicine, Health Supplement 34.3 Single Ingredient Animal Derivative.
READ THIS ENTIRE LEAFLET CAREFULLY BECAUSE IT CONTAINS IMPORTANT INFORMATION FOR YOU
SONTAL Marine Collagen Tripeptide 60 Vegetable CAPSULES is available without a doctor’s prescription.
Nevertheless, you need to use SONTAL Marine Collagen Tripeptide 60 Vegetable Capsules as directed to get the best results.
Keep this leaflet. You may need to read it again.
Do not share SONTAL COLLAGEN Tripeptide 60 Vegetable Capsules with any person.
Ask your pharmacist if you need more information or advice.
The active ingredients are:
Each SONTAL Marine Collagen Tripeptide (CTP) capsule contains 500 mg standardised to 15% Morikol® Collagen Tripeptide equivalent to 75mg tripeptide per capsule, every dose of 2 capsules contains 1000 mg peptides of which 150 mg Tripeptide.
(see 12. IMPORTANT INFORMATION ABOUT THE INGREDIENTS OF SONTAL Tripeptide)
The other ingredients are:
Contains no additives.
Contains o excipients.
Morikol® tripeptide is digestion proof, absorbing intact through exclusive PEPT1 receptors in the intestines. Tripeptides have been found circulating in free form in the bloodstream and in tissue spaces, having shown chemotactic benefits similar to endogenous growth factors like platelet-derived, and basic fibroblast growth factors (PDGF and BFGF).
Furthermore, even dipeptides that are enzymatically cleaved from tripeptide by intestinal peptidases are shown to directly increase the proliferation of fibroblasts, (i.e. collagen synthesizing cells).
Morikol® Collagen Tripeptide, as a low molecular weight collagen peptide (LMWCP), has been the subject of several clinical and preclinical studies, within a dose range of 1-2g/day.
For Morikol® Collagen Tripeptide skin-promoting benefits, a low daily dose of 1g/day is proven to provide collagen rebuilding and anti-ageing properties to the skin.
As a joint-support ingredient, Morikol® Collagen Tripeptide benefit has been established at as low as 2 g/day. The below list of studies has been published on Morikol®.
Pyun H-B, et al. Effects of Collagen Tripeptide Supplement on Photoaging and Epidermal Skin Barrier in UVB-exposed Hairless Mice. Prev Nutr Food Sci. 2012; 17: 245-253
Collagen Tripeptide (CTP) is referred to as the “ESSENTIAL AMINO ACID SEQUENCE”, it has a unique sequence of amino acids specific to collagen fibre and the very (tri-)peptide critical to the formation of collagen.
In clinical studies collagen tripeptide has been shown to;
Collagen Tripeptide has a very low molecular weight of 300 Da, this characteristic makes CTP easy to absorb and highly bioavailable. Di- and Tripeptides from Morikol are absorbed intact increasing bioavailability at the target site where it is available to repair and rebuild damaged collagen tissue as bioactive peptides.
These characteristics have significantly increased the molecules’ clinical value, thereby lowering the effective dose whilst delivering a higher clinical activity per dose compared to the standard 10 000 mg dosages offered by general hydrolysed collagen powders.
When comparing general collagen powders with Morikol® Collagen Tripeptide;
One daily dose of 10 000 mg (10 g) of general collagen powder typically delivers 90% peptides of which <1% tripeptides per dose < 90 mg.
Morikol® at a daily dose of 1 000 mg (1 g) has a minimum concentration standard of 15% tripeptides per dose > 150 mg.
The result is a low convenient daily dose of 1 000 mg or 2 x 500 mg capsules of Morikol® delivers 1,5 times (50%) more Bioactive Collagen Tripeptides than what general collagen powders deliver at 10 000 mg.
SONTAL COLLAGEN Tripeptide 60 Vegetable CAPSULES are primarily used for SKIN, JOINT and BONE health.
PRIMARY INDICATIONS for Skin Health
Dosage 2g: 4 x 500 mg = 2 000 mg Standardised at 15% Tripeptide = 300 mg tripeptides.
Do not take under the following conditions:
Known hypersensitivity or allergy to any ingredients in SONTAL Tripeptide. (see 5. WHAT SONTAL Tripeptide CONTAINS).
Collagen has been consumed by many people across the globe for many years and the safety of it or the by-products of its production have never presented any concerns for safety. Morikol® is produced with food-grade enzymes and is considered a safe product.
Consult with a healthcare practitioner.
SONTAL Tripeptide does not affect the ability to drive or operate machinery.
SONTAL MARINE Collagen Tripeptide contains Morikol®, a patented standardized marine collagen of which 15% tripeptide delivers 150mg of collagen-specific tripeptide per 1 000 mg dose.
Marine Tripetide Collagen, or CTP (Collagen Tripeptide), is a collagen hydrolysate with a tripeptide concentration of more than 15% versus general collagen powders which is less than 1%.
SONTAL MARINE Collagen Tripeptide Capsules contain MoriKol® a 100% piscine-derived, collagen hydrolysate, concentrated to contain a minimum of 15% tripeptides in the highly bioavailable, tripeptide format Gly-X-Y, where X and Y most commonly include proline, hydroxyproline and alanine. CTP is the ESSENTIAL AMINO ACID SEQUENCE unique to collagen.
A Tripeptide is the bioactive component of any collagen powder, the higher the tripeptide density, the more bioactive molecules reach the target tissue in your body.
Always tell your healthcare professional if you are taking any other medicine. This includes complementary or traditional medicines.
No interactions are known.
Do not share medicines that you are taking with any other person.
Always take SONTAL Marine Collagen Tripeptide Capsules exactly as the directions show. You should check with your doctor or pharmacist if you are unsure.
Use in children under 18 years is not recommended.
This product contains collagen amino acid peptides generally regarded as safe.
No known side effects from overdosing with SONTAL Marine Collagen Tripeptide Capsules have been recorded or reported.
If you have missed your dose by only a few hours, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take it at the next regularly scheduled time.
For optimum results, do not miss taking a dose regularly as directed.
No known side effects for SONTAL Marine Collagen Tripeptide Capsules have been recorded or reported.
People have not experienced any side effects when taking SONTAL Marine Collagen Tripeptide Capsules.
Should your general health worsen or if you experience any untoward effects while taking SONTAL Marine Collagen Tripeptide Capsules please consult your doctor, pharmacist or other healthcare professional for advice.
If you notice any side effects not mentioned in this leaflet or if you experience any serious allergic reaction to SONTAL Marine Collagen Tripeptide Capsules, please inform your doctor or pharmacist.
Keep out of reach of children.
Store at or below 25°C, in the original packaging in a dry place. Protect from direct sunlight.
Return all unused medicine to your pharmacist.
Do not dispose of unused medicine in drains or sewerage systems (e.g. toilets).
Do not use it after the expiry date printed on the label or carton.
The capsules are packed into a white plastic 300ml LDPE bottle containing 60 white Vegetable Capsules. The cap is a white plastic screw-on closure with an induction seal fixed to the rim of the bottle.
The body and cap of the capsules are opaque white.
To be allocated by Council upon registration.
This product has not been evaluated by SAHPRA and does not intend to diagnose, treat, cure or prevent any form of illness or disease and should not replace any medication.
A Patient Information Leaflet is available electronically online or can be sent to the consumer by mail, WhatsApp or other preferred methods.
Scan QR Code
Axcel Pharma, William Nicol Street, Pretoria, Gauteng, South Africa
Tel: 012 941 8437
01 October 2022
Orally Available Collagen Tripeptide: Enzymatic Stability, Intestinal Permeability, and Absorption of Gly-Pro-Hyp and Pro-Hyp. Sneha B. Sontakke, Jin-hee Jung, Zhe Piao, and Hye Jin Chung. Journal of Agricultural and Food Chemistry 2016 64 (38), 7127-7133 DOI: 10.1021/acs.jafc.6b02955